Hormone Replacement Therapy and Heart Disease
نویسندگان
چکیده
منابع مشابه
Hormone replacement therapy and coronary heart disease.
Proper use of postmenopausal hormone replacement has been the subject of debate for decades. Prevailing medical opinion has swung between enthusiastic endorsement and extreme caution. The wave of optimism over estrogen's beneficial effects on menopausal symptoms and skeletal health was temporarily set back by the evidence that linked estrogen to endometrial cancer. Once studies showed that prog...
متن کاملCommentary: hormone replacement therapy and coronary heart disease: four lessons.
In 1991, Stampfer and Colditz,1 reviewing epidemiological studies of the effect of postmenopausal oestrogen on coronary heart disease concluded that: ‘... the bulk of evidence strongly supports a protective effect of estrogens that is unlikely to be explained by confounding factors ...’ Their best estimate of the relative risk of coronary heart disease (CHD) in postmenopausal oestrogen users wa...
متن کاملHormone replacement therapy, heart disease, and other considerations.
Multiple observational studies suggest a marked reduction in risk of coronary heart disease (CHD) associated with postmenopausal estrogen use. A new meta-analysis presented here extends these results to estrogen plus progestin regimens. Although the findings from observational studies are strong and consistent, and there are several plausible mechanisms by which estrogen might reduce risk for C...
متن کاملHormone replacement therapy and heart disease: replacing dogma with data.
In 1966, Dr Robert A. Wilson wrote an influential book entitled Feminine Forever that extolled the virtues of postmenopausal hormone replacement therapy (HRT).1 Over the next 3 decades, use of HRT to preserve the health and vitality of postmenopausal women became one of America’s most popular medical treatment paradigms. The enthusiasm for HRT was greatly enhanced by the perception that it coul...
متن کاملHormone replacement therapy and cardiovascular disease.
Oestrogen alone probably confers a degree of protection against ischaemic heart disease and stroke and is appropriate for women requiring hormone replacement therapy (HRT) who have undergone hysterectomy. However, the cardiovascular effects of the progestogens used with oestrogen in the much larger number of women who have not undergone hysterectomy are unknown. Some widely used progestogens ha...
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ژورنال
عنوان ژورنال: Circulation
سال: 2003
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.0000048891.81129.2d